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Visual impairment cell non-autonomously dysregulates brain-wide proteostasis

Loss of hearing or vision has been identified as a significant risk factor for dementia but underlying molecular mechanisms are unknown. In different Drosophila models of blindness, we observe non-autonomous induction of stress granules in the brain and their reversal upon restoration of vision. Str...

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Detalles Bibliográficos
Autores principales: Shekhar, Shashank, Wert, Katherine J, Krämer, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634672/
https://www.ncbi.nlm.nih.gov/pubmed/37961457
http://dx.doi.org/10.1101/2023.10.19.563166

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