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Visual impairment cell non-autonomously dysregulates brain-wide proteostasis
Loss of hearing or vision has been identified as a significant risk factor for dementia but underlying molecular mechanisms are unknown. In different Drosophila models of blindness, we observe non-autonomous induction of stress granules in the brain and their reversal upon restoration of vision. Str...
Autores principales: | Shekhar, Shashank, Wert, Katherine J, Krämer, Helmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634672/ https://www.ncbi.nlm.nih.gov/pubmed/37961457 http://dx.doi.org/10.1101/2023.10.19.563166 |
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