Endogenous opioids gate the locus coeruleus pain generator

The locus coeruleus (LC) plays a paradoxical role in chronic pain. Although largely known as a potent source of endogenous analgesia, increasing evidence suggests injury can transform the LC into a chronic pain generator. We sought to clarify the role of this system in pain. Here, we show optogeneti...

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Detalles Bibliográficos
Autores principales: Norris, Makenzie R., Kuo, Chao-Cheng, Kim, Jenny R., Dunn, Samantha S., Borges, Gustavo, Thang, Loc V., McCall, Jordan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634678/
https://www.ncbi.nlm.nih.gov/pubmed/37961541
http://dx.doi.org/10.1101/2023.10.20.562785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634678/
https://www.ncbi.nlm.nih.gov/pubmed/37961541
http://dx.doi.org/10.1101/2023.10.20.562785

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