Comprehensive single cell aging atlas of mammary tissues reveals shared epigenomic and transcriptomic signatures of aging and cancer

Aging is the greatest risk factor for breast cancer; however, how age-related cellular and molecular events impact cancer initiation is unknown. We investigate how aging rewires transcriptomic and epigenomic programs of mouse mammary glands at single cell resolution, yielding a comprehensive resourc...

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Detalles Bibliográficos
Autores principales: Angarola, Brittany L., Sharma, Siddhartha, Katiyar, Neerja, Gu Kang, Hyeon, Nehar-Belaid, Djamel, Park, SungHee, Gott, Rachel, Eryilmaz, Giray N., LaBarge, Mark A., Palucka, Karolina, Chuang, Jeffrey H., Korstanje, Ron, Ucar, Duygu, Anczukow, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634680/
https://www.ncbi.nlm.nih.gov/pubmed/37961129
http://dx.doi.org/10.1101/2023.10.20.563147

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