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Role of Seasonal Importation and Random Genetic Drift on Selection for Drug-Resistant Genotypes of Plasmodium falciparum in High Transmission Settings

Historically Plasmodium falciparum has followed a pattern of drug resistance first appearing in low transmission settings before spreading to high transmission settings. Several features of low-transmission regions are hypothesized as explanations: higher chance of symptoms and treatment seeking, be...

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Detalles Bibliográficos
Autores principales: Zupko, Robert J., Servadio, Joseph L., Nguyen, Tran Dang, Tran, Thu Nguyen-Anh, Tran, Kien Trung, Somé, Anyirékun Fabrice, Boni, Maciej F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634683/
https://www.ncbi.nlm.nih.gov/pubmed/37961194
http://dx.doi.org/10.1101/2023.10.20.563204