High-resolution CTCF footprinting reveals impact of chromatin state on cohesin extrusion dynamics

DNA looping is vital for establishing many enhancer-promoter interactions. While CTCF is known to anchor many cohesin-mediated loops, the looped chromatin fiber appears to predominantly exist in a poorly characterized actively extruding state. To better characterize extruding chromatin loop structur...

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Detalles Bibliográficos
Autores principales: Sept, Corriene E., Tak, Y. Esther, Cerda-Smith, Christian G., Hutchinson, Haley M., Goel, Viraat, Blanchette, Marco, Bhakta, Mital S., Hansen, Anders S., Joung, J. Keith, Johnstone, Sarah, Eyler, Christine E., Aryee, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634716/
https://www.ncbi.nlm.nih.gov/pubmed/37961446
http://dx.doi.org/10.1101/2023.10.20.563340

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