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Exploring the Roles of RNAs in Chromatin Architecture Using Deep Learning

Recent studies have highlighted the impact of both transcription and transcripts on 3D genome organization, particularly its dynamics. Here, we propose a deep learning framework, called AkitaR, that leverages both genome sequences and genome-wide RNA-DNA interactions to investigate the roles of chro...

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Detalles Bibliográficos
Autores principales: Kuang, Shuzhen, Pollard, Katherine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634726/
https://www.ncbi.nlm.nih.gov/pubmed/37961712
http://dx.doi.org/10.1101/2023.10.22.563498