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Exploring the Roles of RNAs in Chromatin Architecture Using Deep Learning
Recent studies have highlighted the impact of both transcription and transcripts on 3D genome organization, particularly its dynamics. Here, we propose a deep learning framework, called AkitaR, that leverages both genome sequences and genome-wide RNA-DNA interactions to investigate the roles of chro...
Autores principales: | Kuang, Shuzhen, Pollard, Katherine S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634726/ https://www.ncbi.nlm.nih.gov/pubmed/37961712 http://dx.doi.org/10.1101/2023.10.22.563498 |
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