Neutrophil Extracellular Traps have DNAzyme activity that drives bactericidal potential

The mechanisms of bacterial killing by neutrophil extracellular traps (NETs) are unclear. DNA, the largest component of NETs is believed to merely be a scaffold with minimal antimicrobial activity through the charge of the backbone. Here, we report that NETs DNA is beyond a scaffold and produces hyd...

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Detalles Bibliográficos
Autores principales: Ku, Ti-Hsuan, Ram-Mohan, Nikhil, Zudock, Elizabeth J, Abe, Ryuichiro, Yang, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634746/
https://www.ncbi.nlm.nih.gov/pubmed/37961380
http://dx.doi.org/10.1101/2023.10.23.563618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634746/
https://www.ncbi.nlm.nih.gov/pubmed/37961380
http://dx.doi.org/10.1101/2023.10.23.563618

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