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Neutrophil Extracellular Traps have DNAzyme activity that drives bactericidal potential
The mechanisms of bacterial killing by neutrophil extracellular traps (NETs) are unclear. DNA, the largest component of NETs is believed to merely be a scaffold with minimal antimicrobial activity through the charge of the backbone. Here, we report that NETs DNA is beyond a scaffold and produces hyd...
Autores principales: | Ku, Ti-Hsuan, Ram-Mohan, Nikhil, Zudock, Elizabeth J, Abe, Ryuichiro, Yang, Samuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634746/ https://www.ncbi.nlm.nih.gov/pubmed/37961380 http://dx.doi.org/10.1101/2023.10.23.563618 |
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