Platelet proteo-transcriptomic profiling validates mediators of thrombosis and proteostasis in patients with myeloproliferative neoplasms

Patients with chronic Myeloproliferative Neoplasms (MPN) including polycythemia vera (PV) and essential thrombocythemia (ET) exhibit unique clinical features, such as a tendency toward thrombosis and hemorrhage, and risk of disease progression to secondary bone marrow fibrosis and/or acute leukemia....

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Autores principales: Kelliher, Sarah, Gamba, Sara, Weiss, Luisa, Shen, Zhu, Marchetti, Marina, Schieppati, Francesca, Scaife, Caitriona, Madden, Stephen, Bennett, Kathleen, Fortune, Anne, Maung, Su, Fay, Michael, Ní Áinle, Fionnuala, Maguire, Patricia, Falanga, Anna, Kevane, Barry, Krishnan, Anandi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634751/
https://www.ncbi.nlm.nih.gov/pubmed/37961700
http://dx.doi.org/10.1101/2023.10.23.563619

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