Increased intrinsic membrane excitability is associated with hypertrophic olivary degeneration in spinocerebellar ataxia type 1

One of the characteristic areas of brainstem degeneration across multiple spinocerebellar ataxias (SCAs) is the inferior olive (IO), a medullary nucleus that plays a key role in motor learning. In addition to its vulnerability in SCAs, the IO is also susceptible to a distinct pathology known as hype...

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Detalles Bibliográficos
Autores principales: Morrison, Logan M., Huang, Haoran, Handler, Hillary P., Fu, Min, Bushart, David D., Pappas, Samuel S., Orr, Harry T., Shakkottai, Vikram G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634770/
https://www.ncbi.nlm.nih.gov/pubmed/37961407
http://dx.doi.org/10.1101/2023.10.23.563657

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