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Multiple steps of prion strain adaptation to a new host

The transmission of prions across species is a critical aspect of their dissemination among mammalian hosts, including humans. This process often necessitates strain adaptation. In this study, we sought to investigate the mechanisms underlying prion adaptation while mitigating biases associated with...

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Detalles Bibliográficos
Autores principales: Bocharova, Olga, Makarava, Natallia, Pandit, Narayan P., Molesworth, Kara, Baskakov, Ilia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634783/
https://www.ncbi.nlm.nih.gov/pubmed/37961127
http://dx.doi.org/10.1101/2023.10.24.563743