Cargando…

The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth

Mycobacterial glycolipids are important cell envelope structures that drive host-pathogen interactions. Arguably, the most important amongst these are lipoarabinomannan (LAM) and its precursor, lipomannan (LM), which are both trafficked out of the bacterium to the host via unknown mechanisms. An imp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Franklin, Aaron, Layton, Abigail J., Mize, Todd, Salgueiro, Vivian C., Sullivan, Rudi, Benedict, Samuel T., Gurcha, Sudagar S., Anso, Itxaso, Besra, Gurdyal S., Banzhaf, Manuel, Lovering, Andrew L., Williams, Spencer J., Guerin, Marcelo E., Scott, Nichollas E., Prados-Rosales, Rafael, Lowe, Elisabeth C., Moynihan, Patrick J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634837/ https://www.ncbi.nlm.nih.gov/pubmed/37961452 http://dx.doi.org/10.1101/2023.10.26.563968

Ejemplares similares

Inhibition of Escherichia coli glycosyltransferase MurG and Mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics
por: Trunkfield, Amy E., et al.
Publicado: (2010)

Identification of Novel Mt-Guab2 Inhibitor Series Active against M. tuberculosis
por: Usha, Veeraraghavan, et al.
Publicado: (2012)

Ppm1-Encoded Polyprenyl Monophosphomannose Synthase Activity Is Essential for Lipoglycan Synthesis and Survival in Mycobacteria
por: Rana, Amrita K., et al.
Publicado: (2012)

DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid
por: Abrahams, Katherine A., et al.
Publicado: (2023)

Association of Human Antibodies to Arabinomannan With Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction
por: Chen, Tingting, et al.
Publicado: (2016)

Structural characterization and functional properties of a novel lipomannan variant isolated from a Corynebacterium glutamicum pimB′ mutant
por: Mishra, Arun K., et al.
Publicado: (2008)

Automated glycan assembly of arabinomannan oligosaccharides from Mycobacterium tuberculosis
por: Pardo-Vargas, Alonso, et al.
Publicado: (2019)

Mycolic Acid Modification by the mmaA4 Gene of M. tuberculosis Modulates IL-12 Production
por: Dao, Dee N., et al.
Publicado: (2008)

Keto-Mycolic Acid-Dependent Pellicle Formation Confers Tolerance to Drug-Sensitive Mycobacterium tuberculosis
por: Sambandan, Dhinakaran, et al.
Publicado: (2013)

Fluorescent mannosides serve as acceptor substrates for glycosyltransferase and sugar-1-phosphate transferase activities in Euglena gracilis membranes
por: Ivanova, Irina M., et al.
Publicado: (2017)

Enhanced control of Mycobacterium tuberculosis extrapulmonary dissemination in mice by an arabinomannan-protein conjugate vaccine
por: Prados-Rosales, Rafael, et al.
Publicado: (2017)

NSC19723, a Thiacetazone-Like Benzaldehyde Thiosemicarbazone Improves the Efficacy of TB Drugs In Vitro and In Vivo
por: Singh, Padam, et al.
Publicado: (2022)

A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis
por: Kendall, Sharon L, et al.
Publicado: (2007)

The hydrolase LpqI primes mycobacterial peptidoglycan recycling
por: Moynihan, Patrick J., et al.
Publicado: (2019)

The singular Corynebacterium glutamicum Emb arabinofuranosyltransferase polymerises the α(1 → 5) arabinan backbone in the early stages of cell wall arabinan biosynthesis
por: Jankute, Monika, et al.
Publicado: (2018)

Features and protective efficacy of human mAbs targeting Mycobacterium tuberculosis arabinomannan
por: Liu, Yanyan, et al.
Publicado: (2023)

Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component
por: Stoop, Esther J. M., et al.
Publicado: (2011)

Monoclonal antibodies from humans with Mycobacterium tuberculosis exposure or latent infection recognize distinct arabinomannan epitopes
por: Ishida, Elise, et al.
Publicado: (2021)

Structural basis of mammalian mucin processing by the human gut O-glycopeptidase OgpA from Akkermansia muciniphila
por: Trastoy, Beatriz, et al.
Publicado: (2020)

Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase
por: Alderwick, Luke J, et al.
Publicado: (2011)

Effects of infection and disease with Mycobacterium tuberculosis on serum antibody to glucan and arabinomannan: two surface polysaccharides of this pathogen
por: Keitel, Wendy A, et al.
Publicado: (2013)

Expedient synthesis of the heneicosasaccharyl mannose capped arabinomannan of the Mycobacterium tuberculosis cellular envelope by glycosyl carbonate donors
por: Islam, Maidul, et al.
Publicado: (2017)

Combination of immune check inhibitor and immunomodulatory arabinomannan extracted from Mycobacterium tuberculosis: A case report
por: Kobayashi, Kunihiko, et al.
Publicado: (2021)

Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB(2)-AcpM(2)
por: Zhang, Lu, et al.
Publicado: (2020)

Biochemical and Structural Characterization of Mycobacterial Aspartyl-tRNA Synthetase AspS, a Promising TB Drug Target
por: Gurcha, Sudagar S., et al.
Publicado: (2014)

Structure of the priming arabinosyltransferase AftA required for AG biosynthesis of Mycobacterium tuberculosis
por: Gong, Yicheng, et al.
Publicado: (2023)

Lcp1 Is a Phosphotransferase Responsible for Ligating Arabinogalactan to Peptidoglycan in Mycobacterium tuberculosis
por: Harrison, James, et al.
Publicado: (2016)

Mycobacterial cell wall biosynthesis: a multifaceted antibiotic target
por: ABRAHAMS, KATHERINE A., et al.
Publicado: (2018)

Synthesis and recycling of the mycobacterial cell envelope
por: Abrahams, Katherine A, et al.
Publicado: (2021)

Mycobacterial drug discovery
por: Abrahams, Katherine A., et al.
Publicado: (2020)

The role of triacylglycerols and repurposing DGAT1 inhibitors for the treatment of Mycobacterium tuberculosis
por: Moorey, Alice R., et al.
Publicado: (2022)

Synthesis of a Versatile Building Block for the Preparation of 6-N-Derivatized α-Galactosyl Ceramides: Rapid Access to Biologically Active Glycolipids
por: Jervis, Peter J., et al.
Publicado: (2010)

Wifredo Lam
por: Fouchet, Max-Pol
Publicado: (1989)

Wifredo Lam
por: Lam, Wifredo
Publicado: (1978)

Wifredo Lam /
por: Fouchet, Max-Pol

Wifredo Lam
por: Núñez Jiménez, Antonio

Lymphangioleiomyomatosis (LAM)
Publicado: (2017)

Synthesis and biological evaluation of NAS-21 and NAS-91 analogues as potential inhibitors of the mycobacterial FAS-II dehydratase enzyme Rv0636
por: Bhowruth, Veemal, et al.
Publicado: (2008)

Elucidation of a protein-protein interaction network involved in Corynebacterium glutamicum cell wall biosynthesis as determined by bacterial two-hybrid analysis
por: Jankute, Monika, et al.
Publicado: (2014)

LAMS for all pancreatic fluid collections?
por: Bruno, Marco J.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7l1sdqk9ghvmvl8rd8os068tl9