CST–Polymeraseα-primase solves a second telomere end-replication problem

Telomerase solves the end-replication problem by adding G-rich telomeric repeats to the 3ʹ ends of telomeres(1). We report a second end-replication problem affecting the C-rich telomeric repeat strand that is solved by fill-in synthesis by CST–Polymeraseα(Polα)-primase. In vitro replication of linea...

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Detalles Bibliográficos
Autores principales: Takai, Hiro, Aria, Valentina, Borges, Pamela, Yeeles, Joseph T. P., de Lange, Titia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634868/
https://www.ncbi.nlm.nih.gov/pubmed/37961611
http://dx.doi.org/10.1101/2023.10.26.564248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634868/
https://www.ncbi.nlm.nih.gov/pubmed/37961611
http://dx.doi.org/10.1101/2023.10.26.564248

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