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CST–Polymeraseα-primase solves a second telomere end-replication problem
Telomerase solves the end-replication problem by adding G-rich telomeric repeats to the 3ʹ ends of telomeres(1). We report a second end-replication problem affecting the C-rich telomeric repeat strand that is solved by fill-in synthesis by CST–Polymeraseα(Polα)-primase. In vitro replication of linea...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634868/ https://www.ncbi.nlm.nih.gov/pubmed/37961611 http://dx.doi.org/10.1101/2023.10.26.564248 |