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Rapid activation of IL-2 receptor signaling by CD301b(+) DC-derived IL-2 dictates the outcome of helper T cell differentiation

Effector T helper (Th) cell differentiation is fundamental to functional adaptive immunity. Different subsets of dendritic cells (DCs) preferentially induce different types of Th cells, but the fate instruction mechanism for Th type 2 (Th2) differentiation remains enigmatic, as the critical DC-deriv...

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Detalles Bibliográficos
Autores principales:	Tatsumi, Naoya, El-Fenej, Jihad, Davila-Pagan, Alejandro, Kumamoto, Yosuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634899/ https://www.ncbi.nlm.nih.gov/pubmed/37961107 http://dx.doi.org/10.1101/2023.10.26.564276

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