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Insights into Molecular Diversity within the FET Family: Unraveling Phase Separation of the N-Terminal Low Complexity Domain from RNA-Binding Protein EWS

The FET family proteins, which includes FUS, EWS, and TAF15, are RNA chaperones instrumental in processes such as mRNA maturation, transcriptional regulation, and the DNA damage response. These proteins have clinical significance: chromosomal rearrangements in FET proteins are implicated in Ewing fa...

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Detalles Bibliográficos
Autores principales: Johnson, Courtney N., Sojitra, Kandarp A., Sohn, Erich J., Moreno-Romero, Alma K., Baudin, Antoine, Xu, Xiaoping, Mittal, Jeetain, Libich, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634919/
https://www.ncbi.nlm.nih.gov/pubmed/37961424
http://dx.doi.org/10.1101/2023.10.27.564484

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