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Insights into Molecular Diversity within the FET Family: Unraveling Phase Separation of the N-Terminal Low Complexity Domain from RNA-Binding Protein EWS
The FET family proteins, which includes FUS, EWS, and TAF15, are RNA chaperones instrumental in processes such as mRNA maturation, transcriptional regulation, and the DNA damage response. These proteins have clinical significance: chromosomal rearrangements in FET proteins are implicated in Ewing fa...
Autores principales: | Johnson, Courtney N., Sojitra, Kandarp A., Sohn, Erich J., Moreno-Romero, Alma K., Baudin, Antoine, Xu, Xiaoping, Mittal, Jeetain, Libich, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634919/ https://www.ncbi.nlm.nih.gov/pubmed/37961424 http://dx.doi.org/10.1101/2023.10.27.564484 |
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