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Sequence-ensemble-function relationships for disordered proteins in live cells
Intrinsically disordered protein regions (IDRs) are ubiquitous across all kingdoms of life and play a variety of essential cellular roles. IDRs exist in a collection of structurally distinct conformers known as an ensemble. An IDR’s amino acid sequence determines its ensemble, which in turn can play...
Autores principales: | Emenecker, Ryan J., Guadalupe, Karina, Shamoon, Nora M., Sukenik, Shahar, Holehouse, Alex S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634935/ https://www.ncbi.nlm.nih.gov/pubmed/37961106 http://dx.doi.org/10.1101/2023.10.29.564547 |
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