Sequence-ensemble-function relationships for disordered proteins in live cells

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Intrinsically disordered protein regions (IDRs) are ubiquitous across all kingdoms of life and play a variety of essential cellular roles. IDRs exist in a collection of structurally distinct conformers known as an ensemble. An IDR’s amino acid sequence determines its ensemble, which in turn can play...

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Detalles Bibliográficos
Autores principales: Emenecker, Ryan J., Guadalupe, Karina, Shamoon, Nora M., Sukenik, Shahar, Holehouse, Alex S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634935/
https://www.ncbi.nlm.nih.gov/pubmed/37961106
http://dx.doi.org/10.1101/2023.10.29.564547
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