Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer disease

Hub regions in the brain, recognized for their roles in ensuring efficient information transfer, are vulnerable to pathological alterations in neurodegenerative conditions, including Alzheimer Disease (AD). Given their essential role in neural communication, disruptions to these hubs have profound i...

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Detalles Bibliográficos
Autores principales: Tu, Jiaxin Cindy, Millar, Peter R., Strain, Jeremy F., Eck, Andrew, Adeyemo, Babatunde, Daniels, Alisha, Karch, Celeste, Huey, Edward D., McDade, Eric, Day, Gregory S., Yakushev, Igor, Hassenstab, Jason, Morris, John, Llibre-Guerra, Jorge J., Ibanez, Laura, Jucker, Mathias, Mendez, Patricio Chrem, Bateman, Randell J., Perrin, Richard J., Benzinger, Tammie, Jack, Clifford R., Betzel, Richard, Ances, Beau M., Eggebrecht, Adam T., Gordon, Brian A., Wheelock, Muriah D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634945/
https://www.ncbi.nlm.nih.gov/pubmed/37961586
http://dx.doi.org/10.1101/2023.10.29.564633

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