The shared genetic architecture and evolution of human language and musical rhythm

Rhythm and language-related traits are phenotypically correlated, but their genetic overlap is largely unknown. Here, we leveraged two large-scale genome-wide association studies performed to shed light on the shared genetics of rhythm (N=606,825) and dyslexia (N=1,138,870). Our results reveal an in...

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Autores principales: Alagöz, Gökberk, Eising, Else, Mekki, Yasmina, Bignardi, Giacomo, Fontanillas, Pierre, Nivard, Michel G., Luciano, Michelle, Cox, Nancy J., Fisher, Simon E., Gordon, Reyna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634981/
https://www.ncbi.nlm.nih.gov/pubmed/37961248
http://dx.doi.org/10.1101/2023.11.01.564908
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author Alagöz, Gökberk
Eising, Else
Mekki, Yasmina
Bignardi, Giacomo
Fontanillas, Pierre
Nivard, Michel G.
Luciano, Michelle
Cox, Nancy J.
Fisher, Simon E.
Gordon, Reyna L.
author_facet Alagöz, Gökberk
Eising, Else
Mekki, Yasmina
Bignardi, Giacomo
Fontanillas, Pierre
Nivard, Michel G.
Luciano, Michelle
Cox, Nancy J.
Fisher, Simon E.
Gordon, Reyna L.
author_sort Alagöz, Gökberk
collection PubMed
description Rhythm and language-related traits are phenotypically correlated, but their genetic overlap is largely unknown. Here, we leveraged two large-scale genome-wide association studies performed to shed light on the shared genetics of rhythm (N=606,825) and dyslexia (N=1,138,870). Our results reveal an intricate shared genetic and neurobiological architecture, and lay groundwork for resolving longstanding debates about the potential co-evolution of human language and musical traits.
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spelling pubmed-106349812023-11-13 The shared genetic architecture and evolution of human language and musical rhythm Alagöz, Gökberk Eising, Else Mekki, Yasmina Bignardi, Giacomo Fontanillas, Pierre Nivard, Michel G. Luciano, Michelle Cox, Nancy J. Fisher, Simon E. Gordon, Reyna L. bioRxiv Article Rhythm and language-related traits are phenotypically correlated, but their genetic overlap is largely unknown. Here, we leveraged two large-scale genome-wide association studies performed to shed light on the shared genetics of rhythm (N=606,825) and dyslexia (N=1,138,870). Our results reveal an intricate shared genetic and neurobiological architecture, and lay groundwork for resolving longstanding debates about the potential co-evolution of human language and musical traits. Cold Spring Harbor Laboratory 2023-11-02 /pmc/articles/PMC10634981/ /pubmed/37961248 http://dx.doi.org/10.1101/2023.11.01.564908 Text en https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.
spellingShingle Article
Alagöz, Gökberk
Eising, Else
Mekki, Yasmina
Bignardi, Giacomo
Fontanillas, Pierre
Nivard, Michel G.
Luciano, Michelle
Cox, Nancy J.
Fisher, Simon E.
Gordon, Reyna L.
The shared genetic architecture and evolution of human language and musical rhythm
title The shared genetic architecture and evolution of human language and musical rhythm
title_full The shared genetic architecture and evolution of human language and musical rhythm
title_fullStr The shared genetic architecture and evolution of human language and musical rhythm
title_full_unstemmed The shared genetic architecture and evolution of human language and musical rhythm
title_short The shared genetic architecture and evolution of human language and musical rhythm
title_sort shared genetic architecture and evolution of human language and musical rhythm
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634981/
https://www.ncbi.nlm.nih.gov/pubmed/37961248
http://dx.doi.org/10.1101/2023.11.01.564908
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