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Discovery of biaryl macrocyclic peptides with C-terminal β-amino-α-keto acid groups
Advances in genome sequencing and bioinformatics methods have identified myriad biosynthetic gene clusters (BGCs) encoding uncharacterized molecules. By examining genomic databases for BGCs containing a prevalent peptide-binding domain used for the biosynthesis of approximately half of ribosomally s...
Autores principales: | Nguyen, Dinh T., Zhu, Lingyang, Mitchell, Douglas A., van der Donk, Wilfred A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635010/ https://www.ncbi.nlm.nih.gov/pubmed/37965205 http://dx.doi.org/10.1101/2023.10.30.564719 |
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