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Discovery of biaryl macrocyclic peptides with C-terminal β-amino-α-keto acid groups

Advances in genome sequencing and bioinformatics methods have identified myriad biosynthetic gene clusters (BGCs) encoding uncharacterized molecules. By examining genomic databases for BGCs containing a prevalent peptide-binding domain used for the biosynthesis of approximately half of ribosomally s...

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Detalles Bibliográficos
Autores principales: Nguyen, Dinh T., Zhu, Lingyang, Mitchell, Douglas A., van der Donk, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635010/
https://www.ncbi.nlm.nih.gov/pubmed/37965205
http://dx.doi.org/10.1101/2023.10.30.564719

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