Integrated single-nuclei and spatial transcriptomic analysis reveals propagation of early acute vein harvest and distension injury signaling pathways following arterial implantation

BACKGROUND: Vein graft failure (VGF) following cardiovascular bypass surgery results in significant patient morbidity and cost to the healthcare system. Vein graft injury can occur during autogenous vein harvest and preparation, as well as after implantation into the arterial system, leading to the...

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Detalles Bibliográficos
Autores principales: Michaud, Marina E., Mota, Lucas, Bakhtiari, Mojtaba, Thomas, Beena E., Tomeo, John, Pilcher, William, Contreras, Mauricio, Ferran, Christiane, Bhasin, Swati, Pradhan-Nabzdyk, Leena, LoGerfo, Frank W., Liang, Patric, Bhasin, Manoj K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635041/
https://www.ncbi.nlm.nih.gov/pubmed/37961724
http://dx.doi.org/10.1101/2023.10.31.564995

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