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Brain-derived neurotrophic factor contributes to activity-induced muscle pain in male but not female mice

Activity-induced muscle pain increases release of interleukin-1β (IL-1β) in muscle macrophages and the development of pain is prevented by blockade of IL-1β. Brain derived neurotrophic factor (BDNF) is released from sensory neurons in response to IL-1β and mediates both inflammatory and neuropathic...

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Detalles Bibliográficos
Autores principales: Hayashi, Kazuhiro, Lesnak, Joseph B., Plumb, Ashley N., Janowski, Adam J., Smith, Angela F., Hill, Joslyn K., Sluka, Kathleen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635076/
https://www.ncbi.nlm.nih.gov/pubmed/37961342
http://dx.doi.org/10.1101/2023.10.31.565022

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