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Aryl hydrocarbon receptor restricts axon regeneration of DRG neurons in response to injury
Injured neurons sense environmental cues to balance neural protection and axon regeneration, but the mechanisms are unclear. Here, we unveil aryl hydrocarbon receptor (AhR), a ligand-activated bHLH-PAS transcription factor, as molecular sensor and key regulator of acute stress response at the expens...
Autores principales: | Wang, Yiqun, Halawani, Dalia, Estill, Molly, Ramakrishnan, Aarthi, Shen, Li, Friedel, Roland H., Zou, Hongyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635160/ https://www.ncbi.nlm.nih.gov/pubmed/37961567 http://dx.doi.org/10.1101/2023.11.04.565649 |
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