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Flipped C-Terminal Ends of APOA1 Promote ABCA1-dependent Cholesterol Efflux by Small HDLs

BACKGROUND: Cholesterol efflux capacity (CEC) predicts cardiovascular disease (CVD) independently of HDL cholesterol (HDL-C) levels. Isolated small HDL particles are potent promoters of macrophage CEC by the ABCA1 pathway, but the underlying mechanisms are unclear. METHODS: We used model system stud...

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Detalles Bibliográficos
Autores principales:	He, Yi, Pavanello, Chiara, Hutchins, Patrick M., Tang, Chongren, Pourmousa, Mohsen, Vaisar, Tomas, Song, Hyun D., Pastor, Richard W., Remaley, Alan T., Goldberg, Ira J., Costacou, Tina, Davidson, W. Sean, Bornfeldt, Karin E., Calabresi, Laura, Segrest, Jere P., Heinecke, Jay W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635269/ https://www.ncbi.nlm.nih.gov/pubmed/37961344 http://dx.doi.org/10.1101/2023.11.03.23297986

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