YAP-Driven Malignant Reprogramming of Epithelial Stem Cells at Single Cell Resolution

Tumor initiation represents the first step in tumorigenesis during which normal progenitor cells undergo cell fate transition to cancer. Capturing this process as it occurs in vivo, however, remains elusive. Here we employ cell tracing approaches with spatiotemporally controlled oncogene activation...

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Detalles Bibliográficos
Autores principales: Gutkind, J. Silvio, Faraji, Farhoud, Ramirez, Sydney, Clubb, Lauren, Sato, Kuniaki, Quiroz, Paola Anguiano, Galloway, William, Mikulski, Zbigniew, Hoang, Thomas, Medetgul-Ernar, Kate, Marangoni, Pauline, Jones, Kyle, Officer, Adam, Molinolo, Alfredo, Kim, Kenneth, Sakaguchi, Kanako, Califano, Joseph, Smith, Quinton, Klein, Ophir, Tamayo, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635308/
https://www.ncbi.nlm.nih.gov/pubmed/37961717
http://dx.doi.org/10.21203/rs.3.rs-3426301/v1

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