Identification and targeting of treatment resistant progenitor populations in T-cell Acute Lymphoblastic Leukemia

Refractoriness to initial chemotherapy and relapse after remission are the main obstacles to cure in T-cell Acute Lymphoblastic Leukemia (T-ALL). Biomarker guided risk stratification and targeted therapy have the potential to improve outcomes in high-risk T-ALL; however, cellular and genetic factors...

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Detalles Bibliográficos
Autores principales: Tan, Kai, Xu, Jason, Chen, Changya, Vincent, Tiffaney, Pölönen, Petri, Hu, Jianzhong, Yoshimura, Satoshi, Yu, Wenbao, Sussman, Jonathan, Chen, Chia-hui, Li, Elizabeth, Diorio, Caroline, Shraim, Rawan, Newman, Haley, Uppuluri, Lahari, Li, Alexander, Chen, Gregory, Bandyopadhyay, Shovik, Wu, David, Ding, Yang-yang, Xu, Jessica, Lim, Tristan, Hsu, Miles, Thadi, Anusha, Ahn, Kyung Jin, Wu, Chi-Yun, Peng, Jacqueline, Sun, Yusha, Wang, Alice, Mehta, Rushabh, Frank, David, Meyer, Lauren, Loh, Mignon, Raetz, Elizabeth, Chen, Zhiguo, Wood, Brent, Devidas, Meenakshi, Dunsmore, Kimberly, Winter, Stuart, Chang, Ti-Cheng, Wu, Gang, Pounds, Stanley, Zhang, Nancy, Carroll, William, Hunger, Stephen, Bernt, Kathrin, Yang, Jun, Mullighan, Charles, Teachey, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635362/
https://www.ncbi.nlm.nih.gov/pubmed/37961674
http://dx.doi.org/10.21203/rs.3.rs-3487715/v1

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