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Senescent and disease-associated microglia are modifiable features of aged brain white matter

Brain white matter tracts undergo structural and functional changes linked to late-life cognitive decline, but the cellular and molecular contributions to their selective vulnerability are not well defined. In naturally aged mice, we demonstrate that senescent and disease-associated microglia (DAM)...

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Detalles Bibliográficos
Autores principales:	Carver, Chase M., Gomez, Paul T., Rodriguez, Sonia L., Kachergus, Jennifer M., Liu, Yi, Shi, Ji, Tran, Tommy, Wang, Liguo, Melov, Simon, Thompson, E. Aubrey, Schafer, Marissa J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635389/ https://www.ncbi.nlm.nih.gov/pubmed/37961365 http://dx.doi.org/10.21203/rs.3.rs-3467812/v1

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