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AUM302, a novel triple kinase PIM/PI3K/mTOR inhibitor, is a potent in vitro pancreatic cancer growth inhibitor

Pancreatic cancer is one of the leading causes of cancer deaths, with pancreatic ductal adenocarcinoma (PDAC) being the most common subtype. Advanced stage diagnosis of PDAC is common, causing limited treatment opportunities. Gemcitabine is a frequently used chemotherapeutic agent which can be used...

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Detalles Bibliográficos
Autores principales: Ingle, Komala, LaComb, Joseph F., Graves, Lee M., Baines, Antonio T., Bialkowska, Agnieszka B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635512/
https://www.ncbi.nlm.nih.gov/pubmed/37943821
http://dx.doi.org/10.1371/journal.pone.0294065

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