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Allosteric regulation of kinase activity in living cells

The dysregulation of protein kinases is associated with multiple diseases due to the kinases' involvement in a variety of cell signaling pathways. Manipulating protein kinase function, by controlling the active site, is a promising therapeutic and investigative strategy to mitigate and study di...

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Detalles Bibliográficos
Autores principales: Godbole, Shivani Sujay, Dokholyan, Nikolay V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635643/
https://www.ncbi.nlm.nih.gov/pubmed/37943025
http://dx.doi.org/10.7554/eLife.90574

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