Cargando…

Endoplasmic Reticulum Selective Autophagy Alleviates Anthracycline-Induced Cardiotoxicity

BACKGROUND: The administration of anthracycline drugs induces progressive and dose-related cardiac damage through several cytotoxic mechanisms, including endoplasmic reticulum (ER) stress. The unfolded protein response plays a crucial role for mitigating misfolded protein accumulation induced by exc...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakagama, Shun, Maejima, Yasuhiro, Fan, Qintao, Shiheido-Watanabe, Yuka, Tamura, Natsuko, Ihara, Kensuke, Sasano, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635891/
https://www.ncbi.nlm.nih.gov/pubmed/37969644
http://dx.doi.org/10.1016/j.jaccao.2023.05.009