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Artificial axons as a biomimetic 3D myelination platform for the discovery and validation of promyelinating compounds

Multiple sclerosis (MS), a chronic neurodegenerative disease driven by damage to the protective myelin sheath, is currently incurable. Today, all clinically available treatments modulate the immune-mediated symptoms of the disease but they fail to stop neurodegeneration in many patients. Remyelinati...

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Detalles Bibliográficos
Autores principales: Jagielska, Anna, Radzwill, Kristin, Espinosa-Hoyos, Daniela, Yang, Mingyu, Kowsari, Kavin, Farley, Jonathan E., Giera, Stefanie, Byrne, Ann, Sheng, Guoqing, Fang, Nicholas X., Dodge, James C., Pedraza, Carlos E., Van Vliet, Krystyn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636046/
https://www.ncbi.nlm.nih.gov/pubmed/37945646
http://dx.doi.org/10.1038/s41598-023-44675-6