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Artificial axons as a biomimetic 3D myelination platform for the discovery and validation of promyelinating compounds
Multiple sclerosis (MS), a chronic neurodegenerative disease driven by damage to the protective myelin sheath, is currently incurable. Today, all clinically available treatments modulate the immune-mediated symptoms of the disease but they fail to stop neurodegeneration in many patients. Remyelinati...
Autores principales: | Jagielska, Anna, Radzwill, Kristin, Espinosa-Hoyos, Daniela, Yang, Mingyu, Kowsari, Kavin, Farley, Jonathan E., Giera, Stefanie, Byrne, Ann, Sheng, Guoqing, Fang, Nicholas X., Dodge, James C., Pedraza, Carlos E., Van Vliet, Krystyn J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636046/ https://www.ncbi.nlm.nih.gov/pubmed/37945646 http://dx.doi.org/10.1038/s41598-023-44675-6 |
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