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Functional analysis of a putative HER2-associated expressed enhancer, Her2-Enhancer1, in breast cancer cells

HER-2/neu (HER2) is a member of the epidermal growth factor receptors family, encoding a protein with tyrosine kinase activity. Following the gene amplification or increased HER2 transcription, carcinogenesis has been observed in some cancers. Genetic and epigenetic changes occurring in enhancer seq...

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Detalles Bibliográficos
Autores principales: Rojhannezhad, Mahdieh, Soltani, Bahram M., Vasei, Mohammad, Ghorbanmehr, Nassim, Mowla, Seyed Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636096/
https://www.ncbi.nlm.nih.gov/pubmed/37945744
http://dx.doi.org/10.1038/s41598-023-46460-x