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STAT3 phosphorylation at serine 727 activates specific genetic programs and promotes clear cell renal cell carcinoma (ccRCC) aggressiveness

The signal transducer and activator of transcription 3 (STAT3) is a transcription factor mainly activated by phosphorylation in either tyrosine 705 (Y705) or serine 727 (S727) residues that regulates essential processes such as cell differentiation, apoptosis inhibition, or cell survival. Aberrant a...

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Detalles Bibliográficos
Autores principales: Arévalo, J., Campoy, I., Durán, M., Nemours, S., Areny, A., Vall-Palomar, M., Martínez, C., Cantero-Recasens, G., Meseguer, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636117/
https://www.ncbi.nlm.nih.gov/pubmed/37945711
http://dx.doi.org/10.1038/s41598-023-46628-5

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