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Functional alterations of the prefrontal circuit underlying cognitive aging in mice

Executive function is susceptible to aging. How aging impacts the circuit-level computations underlying executive function remains unclear. Using calcium imaging and optogenetic manipulation during memory-guided behavior, we show that working-memory coding and the relevant recurrent connectivity in...

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Detalles Bibliográficos
Autores principales:	Chong, Huee Ru, Ranjbar-Slamloo, Yadollah, Ho, Malcolm Zheng Hao, Ouyang, Xuan, Kamigaki, Tsukasa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636129/ https://www.ncbi.nlm.nih.gov/pubmed/37945561 http://dx.doi.org/10.1038/s41467-023-43142-0

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