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Improving the classification of veterinary thoracic radiographs through inter-species and inter-pathology self-supervised pre-training of deep learning models

The analysis of veterinary radiographic imaging data is an essential step in the diagnosis of many thoracic lesions. Given the limited time that physicians can devote to a single patient, it would be valuable to implement an automated system to help clinicians make faster but still accurate diagnose...

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Autores principales: Celniak, Weronika, Wodziński, Marek, Jurgas, Artur, Burti, Silvia, Zotti, Alessandro, Atzori, Manfredo, Müller, Henning, Banzato, Tommaso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636209/
https://www.ncbi.nlm.nih.gov/pubmed/37945653
http://dx.doi.org/10.1038/s41598-023-46345-z
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author Celniak, Weronika
Wodziński, Marek
Jurgas, Artur
Burti, Silvia
Zotti, Alessandro
Atzori, Manfredo
Müller, Henning
Banzato, Tommaso
author_facet Celniak, Weronika
Wodziński, Marek
Jurgas, Artur
Burti, Silvia
Zotti, Alessandro
Atzori, Manfredo
Müller, Henning
Banzato, Tommaso
author_sort Celniak, Weronika
collection PubMed
description The analysis of veterinary radiographic imaging data is an essential step in the diagnosis of many thoracic lesions. Given the limited time that physicians can devote to a single patient, it would be valuable to implement an automated system to help clinicians make faster but still accurate diagnoses. Currently, most of such systems are based on supervised deep learning approaches. However, the problem with these solutions is that they need a large database of labeled data. Access to such data is often limited, as it requires a great investment of both time and money. Therefore, in this work we present a solution that allows higher classification scores to be obtained using knowledge transfer from inter-species and inter-pathology self-supervised learning methods. Before training the network for classification, pretraining of the model was performed using self-supervised learning approaches on publicly available unlabeled radiographic data of human and dog images, which allowed substantially increasing the number of images for this phase. The self-supervised learning approaches included the Beta Variational Autoencoder, the Soft-Introspective Variational Autoencoder, and a Simple Framework for Contrastive Learning of Visual Representations. After the initial pretraining, fine-tuning was performed for the collected veterinary dataset using 20% of the available data. Next, a latent space exploration was performed for each model after which the encoding part of the model was fine-tuned again, this time in a supervised manner for classification. Simple Framework for Contrastive Learning of Visual Representations proved to be the most beneficial pretraining method. Therefore, it was for this method that experiments with various fine-tuning methods were carried out. We achieved a mean ROC AUC score of 0.77 and 0.66, respectively, for the laterolateral and dorsoventral projection datasets. The results show significant improvement compared to using the model without any pretraining approach.
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spelling pubmed-106362092023-11-11 Improving the classification of veterinary thoracic radiographs through inter-species and inter-pathology self-supervised pre-training of deep learning models Celniak, Weronika Wodziński, Marek Jurgas, Artur Burti, Silvia Zotti, Alessandro Atzori, Manfredo Müller, Henning Banzato, Tommaso Sci Rep Article The analysis of veterinary radiographic imaging data is an essential step in the diagnosis of many thoracic lesions. Given the limited time that physicians can devote to a single patient, it would be valuable to implement an automated system to help clinicians make faster but still accurate diagnoses. Currently, most of such systems are based on supervised deep learning approaches. However, the problem with these solutions is that they need a large database of labeled data. Access to such data is often limited, as it requires a great investment of both time and money. Therefore, in this work we present a solution that allows higher classification scores to be obtained using knowledge transfer from inter-species and inter-pathology self-supervised learning methods. Before training the network for classification, pretraining of the model was performed using self-supervised learning approaches on publicly available unlabeled radiographic data of human and dog images, which allowed substantially increasing the number of images for this phase. The self-supervised learning approaches included the Beta Variational Autoencoder, the Soft-Introspective Variational Autoencoder, and a Simple Framework for Contrastive Learning of Visual Representations. After the initial pretraining, fine-tuning was performed for the collected veterinary dataset using 20% of the available data. Next, a latent space exploration was performed for each model after which the encoding part of the model was fine-tuned again, this time in a supervised manner for classification. Simple Framework for Contrastive Learning of Visual Representations proved to be the most beneficial pretraining method. Therefore, it was for this method that experiments with various fine-tuning methods were carried out. We achieved a mean ROC AUC score of 0.77 and 0.66, respectively, for the laterolateral and dorsoventral projection datasets. The results show significant improvement compared to using the model without any pretraining approach. Nature Publishing Group UK 2023-11-09 /pmc/articles/PMC10636209/ /pubmed/37945653 http://dx.doi.org/10.1038/s41598-023-46345-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Celniak, Weronika
Wodziński, Marek
Jurgas, Artur
Burti, Silvia
Zotti, Alessandro
Atzori, Manfredo
Müller, Henning
Banzato, Tommaso
Improving the classification of veterinary thoracic radiographs through inter-species and inter-pathology self-supervised pre-training of deep learning models
title Improving the classification of veterinary thoracic radiographs through inter-species and inter-pathology self-supervised pre-training of deep learning models
title_full Improving the classification of veterinary thoracic radiographs through inter-species and inter-pathology self-supervised pre-training of deep learning models
title_fullStr Improving the classification of veterinary thoracic radiographs through inter-species and inter-pathology self-supervised pre-training of deep learning models
title_full_unstemmed Improving the classification of veterinary thoracic radiographs through inter-species and inter-pathology self-supervised pre-training of deep learning models
title_short Improving the classification of veterinary thoracic radiographs through inter-species and inter-pathology self-supervised pre-training of deep learning models
title_sort improving the classification of veterinary thoracic radiographs through inter-species and inter-pathology self-supervised pre-training of deep learning models
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636209/
https://www.ncbi.nlm.nih.gov/pubmed/37945653
http://dx.doi.org/10.1038/s41598-023-46345-z
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