Cargando…

Pregnancy and birth complications associations with long-term adverse maternal mental health outcomes: a systematic review and meta-analysis protocol

BACKGROUND: Existing studies have established an association between pregnancy, birth complications, and mental health in the first few weeks postpartum. However, there is no clear understanding of whether pregnancy and birth complications increase the risk of adverse maternal mental outcomes in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Bodunde, Elizabeth O, Buckley, Daire, O'Neill, Eimear, Maher, Gillian M., Matvienko-Sikar, Karen, O'Connor, Karen, McCarthy, Fergus P., Khashan, Ali S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636347/
https://www.ncbi.nlm.nih.gov/pubmed/37954095
http://dx.doi.org/10.12688/hrbopenres.13660.3
_version_ 1785133187445293056
author Bodunde, Elizabeth O
Buckley, Daire
O'Neill, Eimear
Maher, Gillian M.
Matvienko-Sikar, Karen
O'Connor, Karen
McCarthy, Fergus P.
Khashan, Ali S.
author_facet Bodunde, Elizabeth O
Buckley, Daire
O'Neill, Eimear
Maher, Gillian M.
Matvienko-Sikar, Karen
O'Connor, Karen
McCarthy, Fergus P.
Khashan, Ali S.
author_sort Bodunde, Elizabeth O
collection PubMed
description BACKGROUND: Existing studies have established an association between pregnancy, birth complications, and mental health in the first few weeks postpartum. However, there is no clear understanding of whether pregnancy and birth complications increase the risk of adverse maternal mental outcomes in the longer term. Research on maternal adverse mental health outcomes following pregnancy and birth complications beyond 12 months postpartum is scarce, and findings are inconsistent. OBJECTIVE: This systematic review and meta-analysis will examine the available evidence on the association between pregnancy and birth complications and long-term adverse maternal mental health outcomes. METHODS AND ANALYSIS: We will include cohort, cross-sectional, and case-control studies in which a diagnosis of pregnancy and/or birth complication (preeclampsia, pregnancy loss, caesarean section, preterm birth, perineal laceration, neonatal intensive care unit admission, major obstetric haemorrhage, and birth injury/trauma) was reported and maternal mental disorders (depression, anxiety disorders, bipolar disorders, psychosis, and schizophrenia) after 12 months postpartum were the outcomes. A systematic search of PubMed, Embase, CINAHL, PsycINFO, and Web of Science will be conducted following a detailed search strategy until August 2022. Three authors will independently review titles and abstracts of all eligible studies, extract data using pre-defined standardised data extraction and assess the quality of each study using the Newcastle-Ottawa Scale. We will use random-effects meta-analysis for each exposure and outcome variable to calculate overall pooled estimates using the generic inverse variance method. This systematic review will follow the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. ETHICAL CONSIDERATION: The proposed systematic review and meta-analysis is based on published data; ethics approval is not required. The results will be presented at scientific meetings and publish in a peer-reviewed journal. PROSPERO REGISTRATION: CRD42022359017
format Online
Article
Text
id pubmed-10636347
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher F1000 Research Limited
record_format MEDLINE/PubMed
spelling pubmed-106363472023-11-11 Pregnancy and birth complications associations with long-term adverse maternal mental health outcomes: a systematic review and meta-analysis protocol Bodunde, Elizabeth O Buckley, Daire O'Neill, Eimear Maher, Gillian M. Matvienko-Sikar, Karen O'Connor, Karen McCarthy, Fergus P. Khashan, Ali S. HRB Open Res Study Protocol BACKGROUND: Existing studies have established an association between pregnancy, birth complications, and mental health in the first few weeks postpartum. However, there is no clear understanding of whether pregnancy and birth complications increase the risk of adverse maternal mental outcomes in the longer term. Research on maternal adverse mental health outcomes following pregnancy and birth complications beyond 12 months postpartum is scarce, and findings are inconsistent. OBJECTIVE: This systematic review and meta-analysis will examine the available evidence on the association between pregnancy and birth complications and long-term adverse maternal mental health outcomes. METHODS AND ANALYSIS: We will include cohort, cross-sectional, and case-control studies in which a diagnosis of pregnancy and/or birth complication (preeclampsia, pregnancy loss, caesarean section, preterm birth, perineal laceration, neonatal intensive care unit admission, major obstetric haemorrhage, and birth injury/trauma) was reported and maternal mental disorders (depression, anxiety disorders, bipolar disorders, psychosis, and schizophrenia) after 12 months postpartum were the outcomes. A systematic search of PubMed, Embase, CINAHL, PsycINFO, and Web of Science will be conducted following a detailed search strategy until August 2022. Three authors will independently review titles and abstracts of all eligible studies, extract data using pre-defined standardised data extraction and assess the quality of each study using the Newcastle-Ottawa Scale. We will use random-effects meta-analysis for each exposure and outcome variable to calculate overall pooled estimates using the generic inverse variance method. This systematic review will follow the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. ETHICAL CONSIDERATION: The proposed systematic review and meta-analysis is based on published data; ethics approval is not required. The results will be presented at scientific meetings and publish in a peer-reviewed journal. PROSPERO REGISTRATION: CRD42022359017 F1000 Research Limited 2023-10-24 /pmc/articles/PMC10636347/ /pubmed/37954095 http://dx.doi.org/10.12688/hrbopenres.13660.3 Text en Copyright: © 2023 Bodunde EO et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Study Protocol
Bodunde, Elizabeth O
Buckley, Daire
O'Neill, Eimear
Maher, Gillian M.
Matvienko-Sikar, Karen
O'Connor, Karen
McCarthy, Fergus P.
Khashan, Ali S.
Pregnancy and birth complications associations with long-term adverse maternal mental health outcomes: a systematic review and meta-analysis protocol
title Pregnancy and birth complications associations with long-term adverse maternal mental health outcomes: a systematic review and meta-analysis protocol
title_full Pregnancy and birth complications associations with long-term adverse maternal mental health outcomes: a systematic review and meta-analysis protocol
title_fullStr Pregnancy and birth complications associations with long-term adverse maternal mental health outcomes: a systematic review and meta-analysis protocol
title_full_unstemmed Pregnancy and birth complications associations with long-term adverse maternal mental health outcomes: a systematic review and meta-analysis protocol
title_short Pregnancy and birth complications associations with long-term adverse maternal mental health outcomes: a systematic review and meta-analysis protocol
title_sort pregnancy and birth complications associations with long-term adverse maternal mental health outcomes: a systematic review and meta-analysis protocol
topic Study Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636347/
https://www.ncbi.nlm.nih.gov/pubmed/37954095
http://dx.doi.org/10.12688/hrbopenres.13660.3
work_keys_str_mv AT bodundeelizabetho pregnancyandbirthcomplicationsassociationswithlongtermadversematernalmentalhealthoutcomesasystematicreviewandmetaanalysisprotocol
AT buckleydaire pregnancyandbirthcomplicationsassociationswithlongtermadversematernalmentalhealthoutcomesasystematicreviewandmetaanalysisprotocol
AT oneilleimear pregnancyandbirthcomplicationsassociationswithlongtermadversematernalmentalhealthoutcomesasystematicreviewandmetaanalysisprotocol
AT mahergillianm pregnancyandbirthcomplicationsassociationswithlongtermadversematernalmentalhealthoutcomesasystematicreviewandmetaanalysisprotocol
AT matvienkosikarkaren pregnancyandbirthcomplicationsassociationswithlongtermadversematernalmentalhealthoutcomesasystematicreviewandmetaanalysisprotocol
AT oconnorkaren pregnancyandbirthcomplicationsassociationswithlongtermadversematernalmentalhealthoutcomesasystematicreviewandmetaanalysisprotocol
AT mccarthyfergusp pregnancyandbirthcomplicationsassociationswithlongtermadversematernalmentalhealthoutcomesasystematicreviewandmetaanalysisprotocol
AT khashanalis pregnancyandbirthcomplicationsassociationswithlongtermadversematernalmentalhealthoutcomesasystematicreviewandmetaanalysisprotocol