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Identification of DUSP4/6 overexpression as a potential rheostat to NRAS-induced hepatocarcinogenesis

BACKGROUND: Upregulation of the mitogen-activated protein kinase (MAPK) cascade is common in hepatocellular carcinoma (HCC). Neuroblastoma RAS viral oncogene homolog (NRAS) is mutated in a small percentage of HCC and is hitherto considered insufficient for hepatocarcinogenesis. We aimed to character...

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Detalles Bibliográficos
Autores principales:	Klemm, Sophie, Evert, Katja, Utpatel, Kirsten, Muggli, Alexandra, Simile, Maria M., Chen, Xin, Evert, Matthias, Calvisi, Diego F., Scheiter, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636894/ https://www.ncbi.nlm.nih.gov/pubmed/37946160 http://dx.doi.org/10.1186/s12885-023-11577-9

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