The programmed death ligand 1 interactome demonstrates bidirectional signaling coordinating immune suppression and cancer progression in head and neck squamous cell carcinoma

BACKGROUND: The programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) are validated cancer targets; however, emerging mechanisms and impact of PD-L1 intracellular signaling on cancer behavior are poorly understood. METHODS: We investigated the cancer cell intrinsic role of PD-...

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Detalles Bibliográficos
Autores principales: Nieto, Cera, Miller, Bettina, Alzofon, Nathaniel, Chimed, Tugy, Himes, Jack, Joshi, Molishree, Gomez, Karina, Chowdhury, Farshad N, Le, Phuong N, Weaver, Alice, Somerset, Hilary, Morton, J Jason, Wang, Jing H, Wang, Xiao-Jing, Gao, Dexiang, Hansen, Kirk, Keysar, Stephen B, Jimeno, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637037/
https://www.ncbi.nlm.nih.gov/pubmed/37389416
http://dx.doi.org/10.1093/jnci/djad126

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