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Increased mitochondria are responsible for the acquisition of gemcitabine resistance in pancreatic cancer cell lines
Pancreatic ductal adenocarcinoma has a particularly poor prognosis as it is often detected at an advanced stage and acquires resistance to chemotherapy early during its course. Stress adaptations by mitochondria, such as metabolic plasticity and regulation of apoptosis, promote cancer cell survival;...
Autores principales: | Masuo, Hitoshi, Kubota, Koji, Shimizu, Akira, Notake, Tsuyoshi, Miyazaki, Satoru, Yoshizawa, Takahiro, Sakai, Hiroki, Hayashi, Hikaru, Soejima, Yuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637055/ https://www.ncbi.nlm.nih.gov/pubmed/37700464 http://dx.doi.org/10.1111/cas.15962 |
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