Cargando…
YTHDF2 promotes gallbladder cancer progression and gemcitabine resistance via m6A‐dependent DAPK3 degradation
N6‐methyladenosine (m6A) is the most abundant internal modification in eukaryotic RNA and involved in the carcinogenesis of various malignancies. However, the functions and mechanisms of m6A in gallbladder cancer (GBC) remain unclear. In this study, we investigated the role and underlying mechanism...
Autores principales: | Bai, Xuesong, Chen, Jiemin, Zhang, Wenqin, Zhou, Shengnan, Dong, Liangbo, Huang, Jianhao, He, Xiaodong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637062/ https://www.ncbi.nlm.nih.gov/pubmed/37700438 http://dx.doi.org/10.1111/cas.15953 |
Ejemplares similares
-
YTHDF1 promotes mRNA degradation via YTHDF1‐AGO2 interaction and phase separation
por: Li, Jiong, et al.
Publicado: (2021) -
RNA demethylase ALKBH5 prevents pancreatic cancer progression by posttranscriptional activation of PER1 in an m6A-YTHDF2-dependent manner
por: Guo, Xingya, et al.
Publicado: (2020) -
Construction of a prognostic model for HCC based on ferroptosis-related lncRNAs expression and its potential to predict the response and irAEs of immunotherapy
por: Dong, Liangbo, et al.
Publicado: (2023) -
Upregulation of hypothalamic POMC neurons after biliary diversion in GK rats
por: Zhou, Shengnan, et al.
Publicado: (2022) -
SUMOylation of YTHDF2 promotes mRNA degradation and cancer progression by increasing its binding affinity with m(6)A-modified mRNAs
por: Hou, Guofang, et al.
Publicado: (2021)