T cell receptor gene‐modified allogeneic T cells with siRNA for endogenous T cell receptor induce efficient tumor regression without graft‐versus‐host disease

Adoptive immunotherapy using genetically engineered patient‐derived lymphocytes to express tumor‐reactive receptors is a promising treatment for malignancy. However, utilization of autologous T cells in this therapy limits the quality of gene‐engineered T cells, thereby inhibiting the timely infusio...

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Detalles Bibliográficos
Autores principales: Okada, Satomi, Muraoka, Daisuke, Yasui, Kiyoshi, Tawara, Isao, Kawamura, Ayumi, Okamoto, Sachiko, Mineno, Junichi, Seo, Naohiro, Shiku, Hiroshi, Eguchi, Susumu, Ikeda, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637063/
https://www.ncbi.nlm.nih.gov/pubmed/37675556
http://dx.doi.org/10.1111/cas.15954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637063/
https://www.ncbi.nlm.nih.gov/pubmed/37675556
http://dx.doi.org/10.1111/cas.15954

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