On-demand chlorine dioxide solution enhances odontoblast differentiation through desulfation of cell surface heparan sulfate proteoglycan and subsequent activation of canonical Wnt signaling

Heparan sulfate proteoglycans (HSPGs) surround the surface of odontoblasts, and their modification affects their affinity for Wnt ligands. This study proposes applying Matching Transformation System(®) (MA-T), a novel chlorinated oxidant, to enhance dentinogenesis. MA-T treatment in odontoblasts dec...

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Detalles Bibliográficos
Autores principales: Inubushi, Toshihiro, Priyanka, Nag, Watanabe, Masakatsu, Takahashi, Yusuke, Kusano, Shinnosuke, Kurosaka, Hiroshi, Papagerakis, Silvana, Papagerakis, Petros, Hayashi, Mikako, Yamashiro, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637356/
https://www.ncbi.nlm.nih.gov/pubmed/37954207
http://dx.doi.org/10.3389/fcell.2023.1271455

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