A case report of acute myocardial infarction with extremely severe thrombocytopenia after percutaneous coronary intervention

INTRODUCTION: The case report’s purpose is to remind doctors a rare complication named thrombocytopenia of antithrombotic drugs. As a result, severe bleeding or even life-threatening situations may be avoided. PATIENT CONCERNS: A specific case of a patient with acute myocardial infarction, a significant decrease in platelet count was observed after percutaneous coronary intervention. DIAGNOSIS: After ruling out other potential causes, the medical team considered tirofiban-induced thrombocytopenia as a possible explanation. INTERVENTIONS AND OUTCOMES: Through careful monitoring and adjustment of medication, the patient’s platelet count eventually returned to normal. CONCLUSION: To ensure patient safety, it is advised to regularly monitor platelet counts at intervals of 2 to 6 hours before and after administering tirofiban.