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Transcriptional suppression of sphingolipid catabolism controls pathogen resistance in C. elegans
Sphingolipids are required for diverse biological functions and are degraded by specific catabolic enzymes. However, the mechanisms that regulate sphingolipid catabolism are not known. Here we characterize a transcriptional axis that regulates sphingolipid breakdown to control resistance against bac...
Autores principales: | Nasrallah, Mohamad A., Peterson, Nicholas D., Szumel, Elizabeth S., Liu, Pengpeng, Page, Amanda L., Tse, Samantha Y., Wani, Khursheed A., Tocheny, Claire E., Pukkila-Worley, Read |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637724/ https://www.ncbi.nlm.nih.gov/pubmed/37906605 http://dx.doi.org/10.1371/journal.ppat.1011730 |
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