The Aspergillus fumigatus UPR is variably activated across nutrient and host environments and is critical for the establishment of corneal infection

The Aspergillus fumigatus unfolded protein response (UPR) is a two-component relay consisting of the ER-bound IreA protein, which splices and activates the mRNA of the transcription factor HacA. Spliced hacA accumulates under conditions of acute ER stress in vitro, and UPR null mutants are hypovirul...

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Detalles Bibliográficos
Autores principales: Kamath, Manali M., Lightfoot, Jorge D., Adams, Emily M., Kiser, Ryan M., Wells, Becca L., Fuller, Kevin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637725/
https://www.ncbi.nlm.nih.gov/pubmed/37906600
http://dx.doi.org/10.1371/journal.ppat.1011435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637725/
https://www.ncbi.nlm.nih.gov/pubmed/37906600
http://dx.doi.org/10.1371/journal.ppat.1011435

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