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The novel GLP-1/GIP dual agonist DA3-CH improves rat type 2 diabetes through activating AMPK/ACC signaling pathway

Background: Type 2 diabetes mellitus (T2DM) accounts for more than 95% of all diabetes. DA3-CH is a novel dual receptor agonist of glucagon like peptide-1 (GLP-1) and glucose dependent insulin stimulating polypeptide (GIP). The regulatory role of DA3-CH in T2DM has not been reported. Methods: T2DM r...

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Detalles Bibliográficos
Autores principales: Xu, Jing, Chen, Peng, Wu, Dongzhi, Zhou, Qiang, Chen, Sijie, Ding, Xiang, Xiong, Hongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637786/
https://www.ncbi.nlm.nih.gov/pubmed/37851373
http://dx.doi.org/10.18632/aging.205118