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WNT enhancing signals in pancreatic cancer are transmitted by LGR6

The G-protein-coupled receptor LGR6 associates with ligands of the R-Spondin (RSPO) family to potentiate preexisting signals of the canonical WNT pathway. However, its importance in pancreatic ductal adenocarcinoma (PDAC) remains unclear. Here, we show that LGR6 is differentially expressed in variou...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Koch, Dominik T., Hofmann, Felix O., Härtwig, Daniel, Beirith, Iris, Janssen, Klaus Peter, Bazhin, Alexandr V., Niess, Hanno, Werner, Jens, Renz, Bernhard W., Ilmer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637827/
https://www.ncbi.nlm.nih.gov/pubmed/37770230
http://dx.doi.org/10.18632/aging.205101